Induced Menopause

Discover how menopause can be induced from surgical and medical interventions, and how it differs from natural menopause
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A hospital bed on wheels with the head of the bed elevated. MENOPAUSE GUIDANCE
Key Takeaways
  • Induced menopause, unlike naturally occurring menopause, is caused by surgical or medical interventions affecting a woman’s reproductive organs.
  • Surgical menopause occurs when a woman’s ovaries, as well as other reproductive organs, are removed, resulting in an abrupt hormonal decline.
  • Medical menopause occurs following specific therapies and treatments like chemotherapy or pelvic radiation therapy, immediately halting ovarian function.

What is it?

Induced menopause differs significantly from natural menopause, resulting from surgical or medical interventions that directly affect a woman’s reproductive organs rather than age and hormonal changes. These interventions lead to an abrupt cessation of ovarian function, resulting in severe and often immediate menopausal symptoms, particularly for women experiencing premature or early menopause.

Surgical Menopause

Surgical menopause occurs when a woman undergoes a procedure like a bilateral oophorectomy, a bilateral salpingo-oophorectomy, or a radical hysterectomy. All these procedures involve the removal of the ovaries, as well as other reproductive organs. As the ovaries produce eggs (oocytes) and hormones such as estrogen, progesterone, and testosterone responsible for menstrual cycles and pregnancy, hormone production abruptly declines following organ removal, or in some cases, damage during other surgical procedures.

The mentioned procedures may be necessary due to various health conditions such as endometriosis, ovarian cancer (either alone or with a hysterectomy where the cancer has spread to the uterus, or to determine the cancer stage) or to treat certain types of ovarian masses or cysts. Healthcare professionals may also perform these procedures for those with BRCA1 or BRCA2 genes, Lynch Syndrome, or other hereditary genetic mutations as a preventive measure.

Unlike naturally occurring menopause, which gradually develops over years, surgical menopause induces an immediate and often intense onset of symptoms like hot flashes, mood swings, and vaginal dryness. The abrupt hormonal imbalance can also have long-term health implications, including an increased risk of osteoporosis and cardiovascular disease. Given these severe consequences, those facing surgical menopause should consult healthcare professionals about aligned treatment options to manage symptoms effectively.

Medical Menopause

Medical menopause may occur following chemotherapy or pelvic radiation therapy, commonly used to treat cancer. Medical menopause may also result from other treatments like medications used for endometriosis and uterine fibroids that suppress estrogen production or Ovarian Suppression Therapy. This therapy targets hormone receptor-positive breast cancer to shut down the ovaries to suppress estrogen production temporarily. The halt in ovarian function can be temporary or permanent, depending on the extent of treatment and the individual’s response. As such, birth control should be used as appropriate.

Like surgical menopause, medical menopause often leads to severe, sudden symptoms. However, some treatments may result in a gradual onset of symptoms. Because the symptoms can be debilitating, women undergoing medical menopause should work closely with their healthcare professionals to manage them and assess the need for Hormone Replacement Therapy (HRT), or other treatments. Additionally, there may be additional consequences, such as vaginal stenosis, which can be caused by radiation therapy to the pelvis.

Induced menopause, triggered either surgically or medically, presents unique challenges that can affect a woman’s life. In contrast to the gradual onset of naturally occurring menopause, induced menopause causes a sudden hormonal imbalance, leading to immediate and often severe symptoms. This abrupt shift can have both immediate and long-term health consequences, including increased risks of osteoporosis and cardiovascular disease. Moreover, the treatments that result in induced menopause may bring additional health complications. Exploring and implementing appropriate treatment options is crucial in mitigating the effects of induced menopause. Such proactive management is vital in maintaining your overall health, well-being, and life satisfaction during this transition.

Frequently Asked Questions

Can menopause be triggered?

Yes, menopause can be triggered. This is referred to as induced menopause, which can be brought about through surgical or medical interventions. Surgical menopause occurs when a woman undergoes a procedure like a bilateral oophorectomy, where both ovaries are removed, and may be necessary because of various health conditions, such as ovarian cancer.

Medical menopause may occur following pelvic radiation therapy, used to treat gynecologic cancers like ovarian cancer, or medications that suppress estrogen production for women with estrogen-sensitive cancers such as breast cancer, which may be temporary or permanent.

Can induced menopause be reversed?

Induced menopause cannot be reversed. Once the ovaries are removed surgically or their function is halted permanently through surgical or medical intervention, the body cannot naturally resume the production of hormones at pre-menopausal levels.

Some medical treatments that suppress estrogen production may be temporary to halt ovarian function for a specific treatment period. While this may result in immediate menopausal symptoms, once the treatment is stopped, typical ovarian function should resume. Hormone Replacement Therapy (HRT) and other treatments can help manage symptoms and mitigate some health risks associated with induced menopause, however, they cannot reverse induced menopause.

Is induced menopause worse than naturally occurring menopause?

The severity of menopause symptoms can vary greatly among women, whether it is induced or naturally occurring. However, induced menopause, through surgical or medical interventions, leads to an abrupt cessation of ovarian function, resulting in severe and often immediate menopausal symptoms in a short time frame, particularly for women experiencing premature or early menopause.

Naturally occurring menopause, on the other hand, typically results in more gradual, and less severe symptoms over a period of years. The long-term health risks such as osteoporosis can be more significant with induced menopause.

Sources
  • Instant Help for Induced Menopause. The Menopause Society. https://www.menopause.org/for-women/menopauseflashes/menopause-symptoms-and-treatments/instant-help-for-induced-menopause. Accessed October 8, 2023.
  • Medical Causes of Menopause. WebMD. https://www.webmd.com/menopause/medical-procedures-menopause. Accessed October 8, 2023.
  • Nall R. Surgical menopause: Effects, risks, and outlook. https://www.medicalnewstoday.com/articles/317681. Accessed October 8, 2023.
  • Nwadike Riggins V. Surgical Menopause: Benefits, Risks, and Treatment. https://www.healthline.com/health/surgical-menopause. Accessed October 8, 2023.
  • Secoșan C, Balint O, Pirtea L, Grigoraș D, Bălulescu L, Ilina R. Surgically Induced Menopause-A Practical Review of Literature. Medicina (Kaunas). 2019 Aug 14;55(8):482. doi: 10.3390/medicina55080482.
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