Perimenopause Stage

Discover what the first stage of menopause is, when it occurs, hormonal changes, and typical symptoms
Editorial Standards:

Our qualified contributors create and fact-check content following strict guidelines. To learn more, visit the Editorial Standards and Fact-Checking Process pages.

Medical Disclaimer:

The content on this website is for informational and educational purposes only. This website is not a substitute for professional medical advice, diagnosis, or treatment. To learn more, visit the Medical Disclaimer page.

A colored continuous line illustration of a young woman's profile showing part of her hair and neck.
A young woman's profile showing part of her hair and neck. MENOPAUSE GUIDANCE
Key Takeaways
  • Perimenopause is the phase leading up to menopause before a woman’s final period.
  • Many women do not recognize that they are in the perimenopausal stage because of subtle symptoms like mood swings.
  • The duration of perimenopause varies, generally lasting from two to eight years, averaging around four years.

What is it?

Perimenopause (also called the menopause transition or menopausal transition) marks a significant phase in your life as you transition toward menopause. Often starting around 45 years, this period involves hormone fluctuations, specifically in estrogen and progesterone, as well as changes in levels of other hormones like Follicle-Stimulating Hormone (FSH), inhibin, and Anti-Müllerian Hormone (AMH). These hormones, critical for menstrual cycle regulation and fertility during your reproductive years, start to fluctuate and then decline. The period prior to this is called premenopause, when menstrual cycles are regular.

Signs & Symptoms

During the perimenopause stage, it is common for women to experience various symptoms. Often, women do not recognize they are in the perimenopausal stage because symptoms are subtle, common, and sometimes attributed to aging or other medical conditions. Symptoms may include emotional changes such as increased anxiety or mood swings, physical changes like irregular menstrual cycles, and physiological changes due to hormonal shifts. Additionally, Hispanic and Black women may experience these symptoms for a longer duration than Chinese, Japanese, and White women.

To learn more, visit the Symptoms of Menopause page.

Hormonal Changes

Your ovaries begin to produce less estrogen as perimenopause progresses, accompanied by fluctuations in FSH, inhibin, and AMH levels. In the final one to two years of this phase, the decline in estrogen becomes more rapid, often causing symptoms to intensify. Despite this, menstrual cycles continue throughout perimenopause, so pregnancy remains a possibility. For those not wishing to become pregnant, birth control should be used as appropriate until 12 consecutive months without a menstrual period, including spotting.

Women should consult healthcare professionals for an accurate diagnosis and treatment options. The duration of perimenopause can vary significantly, typically ranging from two to eight years, averaging around four years. It may last longer in women who smoke, and those who began the transition before 45 years.

Navigating perimenopause requires understanding and awareness. This stage typically begins in a woman’s mid-40s, characterized by fluctuating levels of estrogen, progesterone, FSH, inhibin, and AMH. Identifying its symptoms, which range from subtle emotional shifts to physical changes like irregular menstrual cycles, can be challenging. These symptoms often vary among different ethnic groups, adding to the complexity of recognition. As estrogen levels drop more rapidly in the later stages, symptoms may intensify, with pregnancy remaining a possibility. Understanding nuances in symptoms and length allows you to remain informed and proactive on your menopause journey.

Frequently Asked Questions

What is perimenopause and when does it start?

Perimenopause (also called menopause transition or menopausal transition) is the first and transitional stage leading up to menopause. The period prior to this is called premenopause when menstrual cycles are regular. Menopause is the second stage, and postmenopause is the third and final stage. Perimenopause is characterized by hormonal fluctuations, namely a reduction in estrogen and progesterone, which are critical hormones for menstrual cycle regulation and fertility.

Typically, perimenopause begins around age 45 as a naturally occurring event. Perimenopause generally lasts two to eight years, with the average duration around four years. Every woman’s experience is unique, with some remaining perimenopausal for a few months, and others up to ten years.

What should you do if you think you are perimenopausal?

If you believe you are perimenopausal, start by keeping track of your menstrual cycles and any symptoms through logs. As menstrual patterns change, a menstrual log helps you keep track of dates, changes, and irregularities. A symptom log helps you keep track of symptoms, even if they seem random and unrelated, providing insight into hormonal changes you may be experiencing.

Next, consult with a healthcare professional, and share your recorded logs. This information offers invaluable insights for an assessment to be made regarding whether you are experiencing menopause, or other related health conditions.

Can you get pregnant during perimenopause?

Yes, pregnancy is still possible during perimenopause, as ovulation, though irregular, continues to occur until menopause is reached. Despite fertility decreasing during this time, contraception should be used where pregnancy is not desired, until menopause is diagnosed. This diagnosis is typically made when a woman has not had a menstrual period for 12 consecutive months.

After menopause, natural conception is no longer possible as ovulation has ceased. For those still looking to conceive, assisted reproductive technologies like In Vitro Fertilization (IVF) using donor eggs may be an option. Reproductive health and contraception should be discussed with a healthcare professional to make informed decisions.

Sources
  • Harlow SD, Burnett-Bowie SM, Greendale GA, Avis NE, Reeves AN, Richards TR, Lewis TT. Disparities in Reproductive Aging and Midlife Health between Black and White women: The Study of Women’s Health Across the Nation (SWAN). Womens Midlife Health. 2022 Feb 8;8(1):3. doi: 10.1186/s40695-022-00073-y.
  • John Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/perimenopause. Accessed October 9, 2023.
  • Perimenopause: Age, Stages, Signs, Symptoms & Treatment. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/21608-perimenopause. Accessed October 9, 2023.
  • Perimenopause – Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/perimenopause/symptoms-causes/syc-20354666. Accessed October 9, 2023.
  • Santoro N, Roeca C, Peters BA, Neal-Perry G. The Menopause Transition: Signs, Symptoms, and Management Options. J Clin Endocrinol Metab. 2021 Jan 1;106(1):1-15. doi: 10.1210/clinem/dgaa764.
About the Author