Naturally Occurring Menopause

Discover when naturally occurring menopause typically occurs, why it occurs, and what to expect
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A colored continuous line illustration of a single branch with a leaf stemming from the top, left and right.
A single branch with a leaf stemming from the top, left and right. MENOPAUSE GUIDANCE
Key Takeaways
  • Naturally occurring menopause typically occurs between 45 and 55 years, signifying the end of ovarian egg production.
  • The decline in hormones, estrogen, and progesterone leads to erratic menstrual cycles, signifying the onset of perimenopause.
  • Early menopause occurs between 40 and 45 years, and late menopause occurs after 55 years.

What is it?

Between 45 and 55 years, most women experience naturally occurring menopause, a significant life event marked by the cessation of ovarian egg (oocyte) production. You are born with a finite number of oocytes, which naturally age and decrease in number over time. Genetic factors also influence this decline, such as family history, like when your mother or sisters experienced menopause, pregnancy, whether you have ever been pregnant, the number of pregnancies, whether you breastfed, lifestyle factors like smoking, and overall health.

What causes it?

As oocytes age and diminish, the concept of ovarian reserve, which is the quality and quantity of remaining eggs, becomes relevant. The ovaries then produce lower levels of essential hormones, estrogen, and progesterone, which have regulated menstruation and prepared the body for potential pregnancy throughout your fertile years. During this transitional phase, known as perimenopause, women may experience anovulatory cycles (menstrual cycles where no egg is released). Biochemical markers like Anti-Müllerian Hormone (AMH) levels tested through the blood can offer insights into the ovarian reserve and impending menopause.

Natural Menopause Types

The hormone decline leads to erratic menstrual cycles, a hallmark of perimenopause. During this stage, estrogen production can fall by over 90%, causing the ovaries to slow down substantially. This decline in fertility begins years before menopause, even though menstruation may still be regular.

Early menopause occurs between 40 and 45 years, and can be naturally occurring or induced by surgical or medical intervention. Early menopause can increase health risks because of the more extended period with lower levels of hormones, such as estrogen, and impact fertility. Health risks and fertility are covered under “Premature & Early Menopause” on the Primary Ovarian Insufficiency (POI) page. Late menopause (or late-onset menopause) occurs after 55 years. The later onset can be naturally occurring, or may be related to genetic factors or certain medical conditions or treatments that affect hormonal balance. Late menopause can increase the risk of certain health conditions, such as ovarian, breast, and uterine cancers, because of prolonged exposure to higher estrogen levels.

When menopause occurs naturally, symptoms are typically gradual, with some of the first symptoms noticed around 45 years, including menstrual changes, mood changes, and sleep disturbances.

After exploring naturally occurring menopause, it becomes clear that this significant life event is multifaceted. It is deeply influenced by genetic factors, lifestyle choices, and overall health, and its onset and progression can vary greatly among women. While menopause brings the cessation of egg production and a decline in essential hormones, it also marks the beginning of a new chapter in a woman’s life. The process is gradual, with symptoms typically appearing around the age of 45. Just as every woman is unique, so is her experience of menopause, and this understanding can empower women to embrace this natural progression in their lives.

Frequently Asked Questions

What is the root cause of menopause?

Menopause is a natural biological process marked by the decrease in ovarian function, leading to lower production of hormones estrogen and progesterone, which regulate menstruation. This hormonal decline causes menstrual periods to become irregular before they eventually cease, signaling the end of a woman’s reproductive years.

The transition involves complex hormonal fluctuations, including changes in the levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), as the ovaries become less responsive. While every woman’s experience is unique, menopause typically includes a range of symptoms and is a normal part of aging.

What age does menopause start?

While the transition to menopause, known as perimenopause, typically begins several years before menopause, the average age of menopause in the United States is 51. The age range for menopause, which is diagnosed following 12 months without a menstrual period, is between 45 and 55 years, however, can also occur earlier or later.

Before 40 years, is called premature menopause, between the ages of 40 and 45 years, early menopause, and after 55 years, late menopause. Menopause that is induced by surgical or medical interventions, such as bilateral oophorectomy and pelvic radiation therapy, has no age range.

Is it better to experience menopause early than late?

There is no definitive better time to experience menopause, as it largely depends on a woman’s individual health and lifestyle factors. Both early and late menopause come with health risks.

Early, including premature menopause, increases the risk of health conditions such as osteoporosis and cardiovascular disease, because of the more extended period with lower estrogen levels. Late menopause may delay some of these health risks, however, the risk of conditions like ovarian, breast, and uterine cancers are increased because of the longer exposure to higher estrogen levels.

Sources
  • Gold EB. The timing of the age at which natural menopause occurs. Obstet Gynecol Clin North Am. 2011 Sep;38(3):425-40. doi: 10.1016/j.ogc.2011.05.002.
  • Gottschalk MS, Eskild A, Hofvind S, Bjelland EK. The relation of number of childbirths with age at natural menopause: a population study of 310 147 women in Norway. Hum Reprod. 2022 Jan 28;37(2):333-340. doi: 10.1093/humrep/deab246.
  • Menopause: What It Is, Age, Stages, Signs & Side Effects. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/21841-menopause. Accessed October 8, 2023.
  • Menopause – Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397. Accessed October 8, 2023.
  • Menopause. World Health Organization: https://www.who.int/news-room/fact-sheets/detail/menopause. Accessed October 8, 2023.
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